Eidgenössische Technische Hochschule Zürich

Relevant Expertise/Experience
• Computational musculoskeletal biomechanics
• Finite element modelling (FEM)
• Medical Device Design
• Participation in large national and international research awards

Role in the project
WP3 leader:
• FEM of the hip joint
• use of co-simulation to predict deleterious conditions for wear and corrosion
• Motion capture and in vivo fluoroscopic analysis of the lower limb
• Aiding design of in vivo animal experiments
• Dissemination and exploitation

The Swiss Federal Institute of Technology Zurich (ETHZ) is one of the leading international universities for technology and the natural sciences. It currently has 17,000 students (3,500 doctoral candidates) from approximately 80 countries. More than 400 professors teach and conduct research in the areas of engineering, architecture, mathematics, natural sciences, system-oriented sciences, and management and social sciences. Founded in 1855, the ETHZ has consistently ranked in the top 20 universities globally and in the top 10 for technical sciences. It has produced 21 Nobel laureates and generated over 80 new patent applications per annum, with more than 240 spin-out companies since 1996.

The Institute for Biomechanics is a multidisciplinary research unit, with three full professorships and a 60-strong team, dedicated to the biomechanical investigation of the human body from macro (organ) to micro (cell) down to nano (molecule) scale. Research employs state-of-the-art biomechanical testing and simulation techniques, cell-level to organ-level culture systems, biochemical and molecular biology analysis, as well as novel micro-structural bio-imaging and visualisation strategies for musculoskeletal tissues, both in vitro and in vivo. The institute is one of the original developers of micro-computed tomography technology that allows imaging of bone and bone/implant interfaces at very high resolution. Institute members are also pioneers in the development of a mobile, motion-tracking fluoroscopy system for dynamic joint imaging. The group has been active in the development of large-scale parallel computing simulations for application in biomechanical structural and fluid dynamic analyses and has extensive experience of the design and refinement of implants for the treatment of musculoskeletal disorders, ranging from conventional orthopaedic implants to biomaterials for tissue engineering applications.

Partner contribution
ETHZ is leader of work package 3 and contributes FEM of the hip joint, use of co-simulation to predict deleterious conditions for wear and corrosion, motion capture and in vivo fluoroscopic analysis of the lower limb, aid in designing in vivo animal experiments, and dissemination and exploitation.